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Description

PE934030: Galβ(1-3)GalNAc-α-PEG3-AzideC20H36N4O13 540. 52 A core 1 T antigen (Gal1 3GalNAc) ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. This compound presents the core 1 T antigen (Gal1 3GalNAc), a tumor associated carbohydrate antigen and ligand for

which is highly expressed on liver hepatocytes and binds GalNAc-containing ligands with high affinity

/ FZD8 (541-549)-STF(541) / Frizzled-8

82 / MUC4 (UniProt ID A0A0G2JMX1) synthetic peptide fragment (Thr1179-Asp1194

The biotin tag enables immobilization on streptavidin/neutravidin-coated platforms for binding studies and glycan arrays

2-Azidoethyl 2-acetamido-2-deoxy-β-D-galactopyranoside

UniProt position 541-550

used to build O-mannosyl glycopeptides

4-Carboxybutyl 2-acetamido-3

C17H32N2O11 / 440

C63H79N3O32 / 1390

39 / A 4-nitrophenyl α-glycoside of nigerose (Glcα1-3Glc)

O-{2-N-acetyl-3-O-(2